New formulations of -cyanoacrylate for biomedical applications
ثبت نشده
چکیده
Introduction * Physical-chemical properties of the -cyanoacrylate * ABSTRACT Currently, new formulations of -cyanoacrylic tissue adhesives, are being studied for the repair of soft and hard tissue in order to improve properties such as: biodegradability, biocompatibility bone flexibility (in the soft tissue applications) and ease of handling. This paper presents a review of scientific literature related to new formulations of -cyanoacrylic adhesives and medical applications.
منابع مشابه
Preparation and Characterization of Poly-(methyl ethyl cyanoacrylate) Particles Containing 5-Aminosalicylic acid
Poly-(alkylcyanoacrylate) ester particles have been used for the preparation of different formulations ranging from ophthalmic delivery systems to cancer chemotherapy carriers in clinic. The aim of this study was to prepare and characterize poly-(methyl ethyl cyanoacrylate) (PMECA) particles containing 5-aminosalicylic acid (5-ASA). PMECA particles were prepared using the inverse emulsification...
متن کاملPreparation and Characterization of Poly-(methyl ethyl cyanoacrylate) Particles Containing 5-Aminosalicylic acid
Poly-(alkylcyanoacrylate) ester particles have been used for the preparation of different formulations ranging from ophthalmic delivery systems to cancer chemotherapy carriers in clinic. The aim of this study was to prepare and characterize poly-(methyl ethyl cyanoacrylate) (PMECA) particles containing 5-aminosalicylic acid (5-ASA). PMECA particles were prepared using the inverse emulsification...
متن کاملIn-vitro evaluation of antibacterial potential of cyanoacrylate tissue adhesives for intraoral wound closure
Background: Cyanoacrylate tissue adhesives have been used as a substitute to silk for intraoral wound closure. Placement of sutures provides a corridor for accumulation of microorganisms into tissue which leads to infection. Cyanoacrylate-based adhesives exhibit many properties of an ideal wound closure agent, minimizing the problems generated by suturing thread. The antimicrobial properties of...
متن کاملQuantitative assessment of polymerization-binding mechanics of cyanoacrylates: model development and validation.
BACKGROUND AND PURPOSE Although commonly acknowledged as paramount in significance, the mechanics of cyanoacrylate polymerization remain poorly characterized and quantified for clinical applications. This prompted development of a simplistic model for the systematic study of polymerization and binding behaviors of cyanoacrylates. METHODS A sliding bed apparatus was constructed that linked a s...
متن کاملSynthesis of poly(alkyl cyanoacrylate)-based colloidal nanomedicines.
Nanoparticles developed from poly(alkyl cyanoacrylate) (PACA) biodegradable polymers have opened new and exciting perspectives in the field of drug delivery due to their nearly ideal characteristics as drug carriers in connection with biomedical applications. Thanks to the direct implication of organic chemistry, polymer science and physicochemistry, multiple PACA nanoparticles with different f...
متن کامل